Effects of methylphenidate on subjective sleep parameters in adults with ADHD: a prospective, non-randomized, non-blinded 6-week trial. (3rd January 2023)

• Record Type: Journal Article
• Authors: Low, Ann-Marie; Vangkilde, Signe; le Sommer, Julijana; Fagerlund, Birgitte; Glenthøj, Birte; Jepsen, Jens Richardt Møllegaard; Habekost, Thomas
• Is Part Of: Nordic journal of psychiatry. Volume 77:Number 1(2023)
• Page Start: 102
• Page End: 107
• Publication Date: 2023-01-03
• Subjects: Adult ADHD -- methylphenidate -- self-report -- sleep; Psychopharmacology -- Periodicals; Psychotherapy -- Periodicals; Psychiatry -- Periodicals; Psychiatry -- Scandinavia -- Periodicals; 616.89
• DOI: 10.1080/08039488.2022.2080253
• Languages: English
• ISSNs: 0803-9488

Abstract

Abstract: Objective: Methylphenidate is a first-line treatment for ADHD; its contribution to sleep problems in adult ADHD is currently unclear. This study investigates (a) subjective sleep disturbances in a group of initially stimulant medication-naïve adults with ADHD and (b) reported changes in sleep problems after 6 weeks of methylphenidate treatment. Method: A prospective, non-randomized, non-blinded, 6-week follow-up study utilising a self-report measure. Results: We found (1) a large difference in reported sleep quality between methylphenidate medication-naïve patients and controls at baseline, (2) a marked improvement in patients after methylphenidate medication, and (3) largest improvement for patients with the poorest reported sleep at baseline. Conclusion: The study indicates that treatment with methylphenidate increases subjective sleep quality for at least some adults with ADHD.