Efficacy of Yiqi Yangyin Jiedu decoction in postoperative patients with thyroid cancer: A protocol for systematic review and meta-analysis. Issue 50 (16th December 2022)

• Record Type: Journal Article
• Authors: Li, Qiao; Zhang, Qiuju; Liu, Yili; Zhao, Shan; Zhang, Bo; Xie, Bingxin
• Is Part Of: Medicine. Volume 101:Issue 50(2022)
• Page Start: e31803
• Publication Date: 2022-12-16
• Subjects: meta-analysis -- protocol -- recurrence -- survival -- systematic review -- Yiqi Yangyin Jiedu decoction; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Geneeskunde; Medicine; Periodicals; Periodicals; 610.5
• DOI: 10.1097/MD.0000000000031803
• Languages: English
• ISSNs: 0025-7974

Abstract

Abstract : Background: There is no evidence-based data to confirm the efficacy of Yiqi Yangyin Jiedu Decoction (YYJD) in postoperative thyroid cancer patients. Therefore, in order to provide new evidence-based medical evidence for clinical treatment, we used this protocol to conduct a systematic review and meta-analysis to evaluate the efficacy and safety of YYJD in postoperative patients with thyroid cancer. Methods: This systematic review and meta-analysis has been prospectively registered in the PROSPERO (No. CRD42022365826). Six databases, including Medicine, Embase, Cochrane, CNKI, Wan Fang, and VIP, will be searched from their inception to February 1, 2023. Clinical controlled studies investigating the efficacy and safety of YYJD in patients after thyroid cancer surgery will all be considered for inclusion. The primary outcomes are tumor recurrence rate and overall survival. The secondary outcomes include treatment-related adverse effects, length of hospital stay, and patient satisfaction. All data will be analyzed using R version 3.4.3 to calculate pooled standardized mean differences for outcomes. Data that can not be retrieved will be interpreted from graphs using digital ruler software. Results: The results of this paper will fill a gap in the literature regarding this project. Conclusion: We assume that the YYJD has a positive effect.