Vaping-induced metabolomic signatures in the circulation of mice are driven by device type, e-liquid, exposure duration and sex. Issue 3 (12th July 2021)

• Record Type: Journal Article
• Authors: Moshensky, Alexander; Du, Mulong; Shin, John; Advani, Ira; Gunge, Deepti; Mathew, Denzil; Alkolla, Rita; Du, Ashley; Javier, Christian; Ma, Lauren; Tran, Albert; Nguyen, Nicholas; Olay, Jarod; Nilaad, Sedtavut; Ding, Jeffrey; Najhawan, Mahan; Watrous, Jeramie D.; Bojanowksi, Christine M.; Jain, Mohit; Christiani, David C.; Crotty Alexander, Laura E.
• Is Part Of: ERJ open research. Volume 7:Issue 3(2021)
• Publication Date: 2021-07-12
• Subjects: Respiratory organs -- Diseases -- Periodicals; Respiration -- Periodicals; Respiration; Respiratory organs -- Diseases; Respiratory organs -- Diseases -- Treatment; Respiratory Tract Diseases; Electronic journals; Fulltext; Internet Resources; Periodicals; Periodical; 616.2005
• DOI: 10.1183/23120541.00229-2021
• Languages: English
• ISSNs: 2312-0541

Abstract

Electronic (e)-cigarette devices have evolved rapidly since the modern version was introduced in 2007 [1, 2]. Inhalation of aerosols generated by these devices has been tied to multiple lung diseases, and diseases and pathology outside the lungs, while the underlying mechanisms driving e-cigarette-associated pathology remain unknown [3–7]. Each type of vaping device (vape pen, box Mod and JUUL), as well as nicotine and flavourings, induces a disparate metabolite profile or signature, such that each device and liquid is likely to lead to its own set of health effects https://bit.ly/3eExKzi