Breast Cancer Metastasis to the Gastrointestinal Tract With Unusual Endoscopic and Histologic Presentations. Issue 12 (26th December 2022)

• Record Type: Journal Article
• Authors: Kimchy, Alexandra V.; Umoren, Mfonsio D.; Rosenberg, Jessica J.; Ilagan, Charmaine; Nithagon, Pichayut; Shafa, Shervin; Jennings, Joseph J.
• Is Part Of: ACG Case Reports Journal. Volume 9:Issue 12(2022)
• Page Start: e00938
• Publication Date: 2022-12-26
• DOI: 10.14309/crj.0000000000000938
• Languages: English
• ISSNs: 2326-3253

Abstract

ABSTRACT: The gastrointestinal (GI) tract is an infrequent site of breast cancer metastasis, but it often poses a diagnostic challenge when it occurs. The symptoms of GI metastases are often nonspecific, and the endoscopic manifestations are variable, requiring tissue biopsies for histologic examination. We report 2 cases of breast cancer metastasizing to the GI tract: a case of human epidermal growth factor receptor 2-positive invasive ductal carcinoma that metastasized to the stomach, a rare location for this histologic subtype, and another case of invasive lobular cell carcinoma that metastasized to the colon with unusual findings of mucosal pallor and edema on colonoscopy.