A Case of Chronic Intranasal Cocaine Abuse Masquerading and Exacerbating Underlying Orbital IgG4-Related Disease. Issue 1 (13th July 2022)

• Record Type: Journal Article
• Authors: Bruce, Carleigh N.; Clark, Thomas J. E.; Ratiani, Mariam; Stahulak, Andrea; Griepentrog, Gregory J.
• Is Part Of: Ophthalmic plastic and reconstructive surgery. Volume 39:Issue 1(2023)
• Page Start: e11
• Page End: e14
• Publication Date: 2022-07-13
• Subjects: Eye -- Surgery -- Periodicals; Ophthalmic plastic surgery -- Periodicals; Reconstructive Surgical Procedures -- Periodicals; Ophthalmologic Surgical Procedures -- Periodicals; Ophthalmology -- Periodicals; Surgery -- Periodicals; 617.70592
• DOI: 10.1097/IOP.0000000000002250
• Languages: English
• ISSNs: 0740-9303

Abstract

Abstract : Chronic cocaine use may lead to widespread intranasal inflammation and necrosis. Cases of cocaine use affecting the orbit have been reported in the literature with a clinical spectrum ranging from inflammation-induced p-anti-cytoplasmic neutrophil autoantibodies positive vasculitis to severe midline destructive lesions resulting in orbital apex syndrome. Here, we present a case of chronic intranasal cocaine abuse with midline destruction that initially obscured diagnosis of, and is hypothesized to have exacerbated, underlying IgG4-Related Disease (IgG4-RD) of the orbit over a 2-year period. Abstract : The authors present a case of severe chronic intranasal cocaine abuse that obscured the diagnosis of, and likely exacerbated, concomitant IgG4-related disease of the orbit.