108 Intraarticular Synovial Angiolipofibroma of the Knee: Report of Two Cases. (11th January 2018)

• Record Type: Journal Article
• Authors: Sellers, Madelie; Wang, Jing; Liu, Weiguo; Soofi, Yousef; Kuechle, Joseph; McGrath, Brian
• Is Part Of: American journal of clinical pathology. Volume 149(2018)Supplement 1
• Page Start: S46
• Page End: S47
• Publication Date: 2018-01-11
• Subjects: Diagnosis, Laboratory -- Periodicals; Pathology -- Periodicals; 616.07
• DOI: 10.1093/ajcp/aqx118.107
• Languages: English
• ISSNs: 0002-9173

Abstract

Abstract: Angiolipofibroma is a rare benign tumor most commonly affecting young male patients in the second and third decade of age. It most commonly involves the forearm, followed by the trunk and upper arm. Some unusual locations that have been reported include head and neck area and colon. We recent encountered two cases of angiolipofibroma of knee within five months. Both cases affected senior men in their 60s and 70s who showed large massive lesions measuring 7 cm and 9 cm, respectively, in their knees by magnetic resonance image study, and there were clinical and radiological concerns for sarcoma. Both patients underwent preoperative biopsies, which showed no evidence of malignancy; however, no definitive diagnoses were rendered. Intraoperatively, the masses appeared to be arising from synovium. Postoperative histological examination demonstrated that the tumors were composed of admixture of proliferative vasculature, fibrous tissue, and fat with chondroid metaplasia and necrosis or myxoid changes. The histologic features are consistent with benign synovial angiolipofibroma. Both patients recovered uneventfully after the operations. As we reviewed the literature, we found only one case report that designates a very similar lesion as an angiolipofibroma-like tumor. We herein report two cases of intraarticular angiolipofibroma of the knee to emphasize the feasible incidence of this entity in the knee, and it should be considered in the differential diagnoses of an intraarticular mass of the knee clinically and radiologically.