Predicting vigilance vulnerability during 1 and 2 weeks of sleep restriction with baseline performance metrics. Issue 1 (25th October 2022)

• Record Type: Journal Article
• Authors: Lo, June C; Ang, Jit Wei A; Koa, Tiffany B; Ong, Ju Lynn; Lim, Julian
• Is Part Of: Sleep advances. Volume 3:Issue 1(2022)
• Publication Date: 2022-10-25
• Subjects: baseline performance -- diffusion drift model -- sleep restriction -- sustained attention -- vigilance -- vulnerability; Sleep disorders -- Periodicals; Circadian rhythms -- Periodicals; 616.8498
• DOI: 10.1093/sleepadvances/zpac040
• Languages: English
• ISSNs: 2632-5012

Abstract

Abstract: Study Objectives: We attempted to predict vigilance performance in adolescents during partial sleep deprivation using task summary metrics and drift diffusion modelling measures (DDM) derived from baseline vigilance performance. Methods: In the Need for Sleep studies, 57 adolescents (age = 15–19 years) underwent two baseline nights of 9-h time-in-bed (TIB), followed by two cycles of weekday sleep-restricted nights (5-h or 6.5-h TIB) and weekend recovery nights (9-h TIB). Vigilance was assessed daily with the Psychomotor Vigilance Task (PVT), with the number of lapses (response times ≥ 500 ms) as the primary outcome measure. The two DDM predictors were drift rate, which quantifies the speed of information accumulation and determines how quickly an individual derives a decision response, and non-decision time range, which indicates within-subject variation in physical, non-cognitive responding, e.g. motor actions. Results: In the first week of sleep curtailment, faster accumulation of lapses was significantly associated with more lapses at baseline ( p = .02), but not the two baseline DDM metrics: drift and non-decision time range ( p > .07). On the other hand, faster accumulation of lapses and greater increment in reaction time variability from the first to the second week of sleep restriction were associated with lower drift ( p < .007) at baseline. Conclusions: Among adolescents, baseline PVT lapses can predict inter-individual differences in vigilance vulnerability during 1 week of sleep restriction on weekdays, while drift more consistently predicts vulnerability during more weeks of sleep curtailment. Clinical Trial Information: Effects of Napping in Sleep-Restricted Adolescents, clinicaltrials.gov, NCT02838095. The Cognitive and Metabolic Effects of Sleep Restriction in Adolescents (NFS4), clinicaltrials.gov, NCT03333512.