Scedosporium apiospermum invasive rhinosinusitis in an elderly patient: diagnosis and treatment. Issue 12 (December 2022)

• Record Type: Journal Article
• Authors: Liang, Yibo; Xiong, Xin; Zhang, Chenting; Wang, Wei; Zhang, Guimin
• Is Part Of: Heliyon. Volume 8:Issue 12(2022)
• Publication Date: 2022-12
• Subjects: Scedosporium apiospermum -- Invasive fungal rhinosinusitis -- Metagenomic next-generation sequencing; Research -- Periodicals; Medical sciences -- Periodicals; Natural history -- Periodicals; Social sciences -- Periodicals; Earth sciences -- Periodicals; Physical sciences -- Periodicals; 507.2
• DOI: 10.1016/j.heliyon.2022.e12476
• Languages: English
• ISSNs: 2405-8440

Abstract

Abstract: Scedosporium apiospermum is a ubiquitous organism present in the environment and is rarely identified in rhinosinusitis. We report a case of invasive rhinosinusitis with Scedosporium apiospermum which made a definite diagnosis by metagenomic next-generation sequencing (mNGS) from a biopsy sample. The resection of the Scedosporium apiospermum pathological mass was performed with low-temperature plasma radiofrequency ablation. Six months of continuous oral voriconazole treatment was followed. The patient was asymptomatic with no signs of recurrence during the next 1-year follow-up. Abstract : Scedosporium apiospermum ; Invasive fungal rhinosinusitis; Metagenomic next-generation sequencing.