Fluorescence probe with aggregation induced emission effect and application for colormetric detection of endogenous and exogenous hypochlorite. (February 2023)

• Record Type: Journal Article
• Authors: Li, Na-Na; Gao, Yong-E; Xu, Xing-Yu; Qiu, Ping; Gao, Yan; Yan, Miao; Zhang, Qian; Lin, Wan-Ying; Xing, Zhi-Yong; Zong, Zi-Ao
• Is Part Of: Dyes and pigments. Volume 210(2023)
• Publication Date: 2023-02
• Subjects: Aggregation-induced emission (AIE) -- Hypochlorite (ClO−) -- Colormetric detection -- Cell imaging; Dyes and dyeing -- Periodicals; Pigments -- Periodicals; 667.2
• DOI: 10.1016/j.dyepig.2022.110965
• Languages: English
• ISSNs: 0143-7208

Abstract

Abstract: In this work, a colormetric fluorescent probe named NMH, which exhibited aggregation-induced emission (AIE) characteristic in water/EtOH binary solvent was developed based on 2-hydrazinobenzothiazole and 6-methoxy-2-acetonaphthone for sensing hypochlorous acid (HClO) with high selectivity and sensitivity (detection limit: 1.7 nM). Also, NMH had a strong anti-interference effect and a fluorescence color change in the solution which can be seen by the"naked eye". Moreover, NMH could be applied to detect ClO − in tap water and test paper. In addition, cell imaging experiments showed that probe NMH could detect endogenous and exogenous ClO − in A549 cells successfully. Graphical abstract: In this work, probe NMH, which exhibited aggregation-induced emission (AIE) characteristic in water/EtOH binary solvent was developed and could be applied to detect ClO − with colormetric response in tap water, test paper and living cells. Image 1 Highlights: A selective fluorescent probe NMH with aggregation-induced emission characteristic was developed by one step reaction. The probe NMH could be widely used as a "naked eye" probe for detecting ClO − by the color changes from purple to blue. The probe NMH could detect endogenous and exogenous ClO − in A549 cells successfully.