Gutsy sensations modulate intestinal disease. Issue 1 (January 2023)

• Record Type: Journal Article
• Authors: Cao, Wang; Belz, Gabrielle
• Is Part Of: Trends in immunology. Volume 44:Issue 1(2023)
• Page Start: 1
• Page End: 3
• Publication Date: 2023-01
• Subjects: enteric nervous system -- gastrointestinal immune response -- gut immunology -- mast cells -- neuroimmunology; Immunology -- Periodicals; 571.96
• DOI: 10.1016/j.it.2022.11.007
• Languages: English
• ISSNs: 1471-4906

Abstract

Abstract: Pain is a hallmark symptom associated with intestinal inflammation. Two related articles published in Cell by Zhang et al. and by Yang et al. now report how sensory neurons in the gut, the most heavily innervated organ in the human body, flag bacterial pathogens to shape the composition of the gut microbiome and to trigger immunoregulatory mechanisms.