Addition of an adipose marker to the organ tissue identification mRNA assay. (December 2022)

• Record Type: Journal Article
• Authors: van den Berge, Margreet; Sijen, Titia
• Is Part Of: Forensic science international. Volume 8(2022)
• Page Start: 32
• Page End: 34
• Publication Date: 2022-12
• Subjects: Forensic science -- MRNA profiling -- Organ tissue identification -- Adipose tissue; Forensic genetics -- Periodicals; Forensic Genetics -- Periodicals; Electronic journals; 614.1
• DOI: 10.1016/j.fsigss.2022.09.012
• Languages: English
• ISSNs: 1875-1768

Abstract

Abstract: At the Netherlands Forensic Institute, mRNA profiling for the purpose of organ tissue identification is frequently requested in casework. The previous version of the assay (denoted Organtyper) lacked markers for identifying adipose tissue, while this was occasionally questioned in casework. Here, three potential adipose markers are examined before incorporating one into the final Organtyper assay. The added value of the adipose marker becomes clear from looking at casework results.