Merkel cell carcinoma in a patient with GATA2 deficiency: a novel association with primary immunodeficiency. (1st January 2016)

• Record Type: Journal Article
• Authors: Crall, C.; Morley, K.W.; Rabinowits, G.; Schmidt, B.; Broyles, A. Dioun; Huang, J.T.
• Is Part Of: British journal of dermatology. Volume 174:Number 1(2016)
• Page Start: 169
• Page End: 171
• Publication Date: 2016-01-01
• Subjects: Dermatology -- Periodicals; Skin -- Diseases -- Periodicals; 616.5
• DOI: 10.1111/bjd.14062
• Languages: English
• ISSNs: 0007-0963

Abstract

Summary: A 55‐year‐old woman with GATA2 deficiency and neurofibromatosis 1 was diagnosed with Merkel cell carcinoma (MCC). This polyomavirus‐associated cutaneous malignancy has previously been associated with immunosuppression and acquired immunodeficiencies such as HIV/AIDS. However, MCC has not been previously reported in the setting of underlying primary or inherited immunodeficiency.