Management of early graft candidiasis in a kidney transplant recipient. Issue 11 (22nd November 2022)

• Record Type: Journal Article
• Authors: Tan, Jaimee; Wild, Abigail; Reid, Graeme; Shantier, Mohamed
• Is Part Of: BMJ case reports. Volume 15:Issue 11(2022)
• Publication Date: 2022-11-22
• Subjects: Renal transplantation -- Infections -- Renal system; Medicine -- Case studies -- Periodicals; 610.5
• DOI: 10.1136/bcr-2022-250890
• Languages: English
• ISSNs: 1757-790X

Abstract

Abstract : Balancing adequate immunosuppression with the risk of infection after renal transplantation remains a challenge. The presence of comorbidities adds to the challenge. Although infrequent, invasive fungal infections result in high morbidity and mortality risk in renal transplant recipients. This can be attributed to the intense immunosuppression in the first 6 months after renal transplantation, minimal symptomatology and the high mortality associated with fungal infections. Due to minimal available evidence, clinical judgement guides management of graft candidiasis. There is a need to develop evidence-based management guidelines for the treatment of fungal infections in renal transplants. Here, we report a case of early-onset candidiasis in a transplanted kidney and present the histological findings, multidisciplinary discussions and treatment given.