Toward Hierarchical Assembly of Aligned Cell Sheets into a Conical Cardiac Ventricle Using Microfabricated Elastomers (Adv. Biology 11/2022). Issue 11 (21st November 2022)

• Record Type: Journal Article
• Authors: Mohammadi, Mohammad Hossein; Okhovatian, Sargol; Savoji, Houman; Campbell, Scott B.; Lai, Benjamin Fook Lun; Wu, Jun; Pascual‐Gil, Simon; Bannerman, Dawn; Rafatian, Naimeh; Li, Ren‐Ke; Radisic, Milica
• Is Part Of: Advanced biology. Volume 6:Issue 11(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-11-21
• Subjects: Molecular biology -- Periodicals; Systems biology -- Periodicals; Biological systems -- Periodicals; Biotechnology -- Periodicals; Bioengineering -- Periodicals; Biomedical engineering -- Periodicals; 660.6
• DOI: 10.1002/adbi.202270111
• Languages: English
• ISSNs: 2701-0198

Abstract

Abstract : Conical Cardiac Ventricle In article 2101165, Radisic and co‐workers describe a multilayered in vitro model of a cardiac ventricle composed of three layers with different pattern orientations representing the physiological cardiac fiber architecture. This model is fabricated by rolling a 2D elastomeric scaffold seeded with cardiomyocytes around a central mandrel and is capable of pumping fluid.