Base-promoted radical decarboxylative coupling of N, N-Difluorobenzenesulfonamide and cinnamic acid. (9th January 2023)

• Record Type: Journal Article
• Authors: Fei, Fan; Yang, Xianjin
• Is Part Of: Tetrahedron. Volume 130(2023)
• Publication Date: 2023-01-09
• Subjects: Base-promoted -- N, N-difluorobenzenesulfonamide -- Metal and oxidant-free; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tet.2022.133169
• Languages: English
• ISSNs: 0040-4020

Abstract

Abstract: A base-promoted decarboxylative sulfonylation of cinnamic acids with N, N-difluorobenzenesulfonamide (DFBSAs) is developed. This study offers a highly efficient metal and oxidant-free strategy for the preparation of ( E )-vinyl sulfones. Moreover, the transformation is proposed to proceed via a radical process and exhibits broad substrate scopes and good functional group tolerance. Graphical abstract: To create your abstract, type over the instructions in the template box below. Fonts or abstract dimensions should not be changed or altered. Image 1