Reactive Eccrine Syringofibroadenomatosis Associated With Venous Leg Ulcers: A Case Report and Literature Review. (March 2023)

• Record Type: Journal Article
• Authors: Tedbirt, Billal; Carvalho, Priscille; Boulard, Claire; Tetart, Florence; Deschamps-Huvier, Aurélie; Chenal, Pierre; Courville, Philippe; Cellier, Lucie; Joly, Pascal
• Is Part Of: International journal of lower extremity wounds. Volume 22:Number 1(2023)
• Page Start: 135
• Page End: 138
• Publication Date: 2023-03
• Subjects: eccrine syringofibroadenomatosis -- venous leg ulcers -- adnexal tumor; Leg -- Wounds and injuries -- Periodicals; Wounds and injuries -- Prevention -- Periodicals; Leg -- Ulcers -- Periodicals; Wound healing -- Periodicals; 617.584
• DOI: 10.1177/1534734620966900
• Languages: English
• ISSNs: 1534-7346

Abstract

Eccrine syringofibroadenoma (ESFA) is a rare adnexal tumor deriving from the acrosyringeal portion of the eccrine duct. Five subtypes of ESFA were described including a reactive form. Reactive ESFAs are associated with inflammatory and neoplastic dermatoses. In this article, we report the case of a 90-year-old woman presenting with 3 leg ulcers evolving for 2 years surrounded by large verrucous and eczematous lesions. Multiple skin biopsies showed anastomosing epithelial cords connected to the epidermis consistent with ESFA. We identified 8 cases of ESFA associated with chronic leg ulcers in the literature and reviewed their main clinical and histological features.