Higher alveolar nitric oxide in COPD is related to poorer physical capacity and lower oxygen saturation after physical testing. Issue 2 (1st August 2019)

• Record Type: Journal Article
• Authors: Högman, Marieann; Thornadtsson, Alexandra; Bröms, Kristina; Janson, Christer; Lisspers, Karin; Ställberg, Björn; Hedenström, Hans; Malinovschi, Andrei
• Is Part Of: European respiratory journal. Volume 54:Issue 2(2019)
• Publication Date: 2019-08-01
• Subjects: Respiratory organs -- Diseases -- Periodicals; Respiration -- Periodicals; 616.2
• DOI: 10.1183/13993003.00263-2019
• Languages: English
• ISSNs: 0903-1936

Abstract

Exhaled nitric oxide ( F ENO ) is an inflammatory marker used in asthma management but its clinical role in chronic obstructive pulmonary disease (COPD) is less defined. F ENO represents the NO production in the airways. Various mathematical models have been used to gain information regarding peripheral NO from the lung [1]. NO from the gas exchange area is referred to as alveolar NO ( C ANO ). C ANO has been shown to be increased in symptomatic asthmatic subjects [2 ]; whereas in COPD, there is an alveolar destruction with emphysema and higher values of C ANO have been reported [3–5]. Nitric oxide from the gas exchange area, but not from the airways, is increased in subjects with chronic obstructive pulmonary disease with low oxygen saturation after physical testing http://bit.ly/2ItUJy6