Looking at the COPD spectrum through "PRISm". Issue 1 (2nd January 2020)

• Record Type: Journal Article
• Authors: Adibi, Amin; Sadatsafavi, Mohsen
• Is Part Of: European respiratory journal. Volume 55:Issue 1(2020)
• Publication Date: 2020-01-02
• Subjects: Respiratory organs -- Diseases -- Periodicals; Respiration -- Periodicals; 616.2
• DOI: 10.1183/13993003.02217-2019
• Languages: English
• ISSNs: 0903-1936

Abstract

COPD is a major burden globally. According to the Global Burden of Disease study, COPD caused 3.2 million deaths in 2015, accounting for 5% of all deaths worldwide, making it the third leading cause of death in the world [1]. The Global Initiative for Chronic Obstructive Lung Disease (GOLD) defines spirometrically confirmed COPD based on a forced expiratory volume during the first second (FEV1 ) to a forced vital capacity (FVC) ratio smaller than 0.7 [2]. The severity of airflow obstruction is further defined through GOLD severity grades based on the ratio of FEV1 to its predicted value, with GOLD 1, 2, 3 and 4 defined around cut-off points of 80%, 50%, and 30% [2]. Preserved ratio impaired spirometry (PRISm) is a prevalent, neglected condition whose prognosis is close to that of COPD http://bit.ly/2Oydvq1