Continuous positive airway pressure in COVID-19 patients with moderate-to-severe respiratory failure. Issue 2 (18th February 2021)

• Record Type: Journal Article
• Authors: Brusasco, Claudia; Corradi, Francesco; Di Domenico, Antonia; Raggi, Francesca; Timossi, Graziano; Santori, Gregorio; Brusasco, Vito
• Other Names: author non-byline.; Antonucci Giancarlo author non-byline.; Blasi Vacca Elisabetta author non-byline.; Bobbio Nicoletta author non-byline.; Feasi Marcello author non-byline.; Forfori Francesco author non-byline.; Guido Patrizia author non-byline.; Lattuada Marco author non-byline.; Mameli Leila author non-byline.; Parodi Donatella author non-byline.; Pienovi Roberta author non-byline.; Pontali Emanuele author non-byline.; Scirocco Maria Concetta author non-byline.; Terrile Marina author non-byline.
• Is Part Of: European respiratory journal. Volume 57:Issue 2(2021)
• Publication Date: 2021-02-18
• Subjects: Respiratory organs -- Diseases -- Periodicals; Respiration -- Periodicals; 616.2
• DOI: 10.1183/13993003.02524-2020
• Languages: English
• ISSNs: 0903-1936

Abstract

Noninvasive ventilation (NIV) and continuous positive airway pressure (CPAP) are recommended for acute hypoxaemic respiratory failure (AHRF) due to cardiogenic pulmonary oedema but no recommendation has been made for viral pandemics, because of the lack of randomised studies showing their efficacy and concerns of infection dissemination [1]. Early after the coronavirus disease 2019 (COVID-19) outbreak in Italy, there was an expert consensus in favour of CPAP and NIV as first-line treatments for the associated AHRF [2]. However, few studies used unspecified NIV in a minority of patients without detailed results [3–5]. CPAP was the object of two short reports with differing results [6, 7]. Thus, their value in COVID-19 remains to be established. CPAP can be successfully used in a number of COVID-19 patients with hypoxaemic respiratory failure and gas exchange and radiological findings similar to those generally considered to be indications for invasive mechanical ventilation https://bit.ly/2GpBx6a