Urine Biomarkers Neutrophil Gelatinase-Associated Lipocalin (NGAL) and Kidney Injury Molecule-1 (KIM-1) Have Different Patterns in Heart Failure Exacerbation. Issue 8 (January 2013)

• Record Type: Journal Article
• Authors: Park, Meyeon; Vittinghoff, Eric; Liu, Kathleen D.; Shlipak, Michael G.; Hsu, Chi-yuan
• Is Part Of: Biomarker insights. Volume 2013:Issue 8(2013)
• Publication Date: 2013-01
• Subjects: acute kidney injury -- urine biomarkers -- heart failure; Biochemical markers -- Periodicals; 572.43
• DOI: 10.4137/BMI.S11479
• Languages: English
• ISSNs: 1177-2719

Abstract

Individuals with acute heart failure exacerbation often experience a deterioration in renal function. We sought to determine whether this deterioration is ischemic in nature and detectable by sensitive urine biomarkers neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1). We measured serial biomarker levels and evaluated the associations of these biomarkers with renal recovery in a cohort of hospitalized patients with acute heart failure exacerbation.