Observational study of inhaled corticosteroid treatment for improved expiratory variability index in steroid-naïve asthmatic children. Issue 1 (7th February 2021)

• Record Type: Journal Article
• Authors: Burman, Janne; Malmberg, Pekka; Seppä, Ville-Pekka; Jartti, Tuomas; Remes, Sami; Mickelsson, Ove; Pelkonen, Anna S.; Mäkelä, Mika J.
• Is Part Of: ERJ open research. Volume 8:Issue 1(2022)
• Publication Date: 2021-02-07
• Subjects: Respiratory organs -- Diseases -- Periodicals; Respiration -- Periodicals; Respiration; Respiratory organs -- Diseases; Respiratory organs -- Diseases -- Treatment; Respiratory Tract Diseases; Electronic journals; Fulltext; Internet Resources; Periodicals; Periodical; 616.2005
• DOI: 10.1183/23120541.00499-2021
• Languages: English
• ISSNs: 2312-0541

Abstract

The Lancet Asthma Commission calls for objective measurements to support asthma diagnosis, especially for children [1]. The expiratory variability index (EVI) is a novel method of testing lung function that can be measured passively at night with an impedance pneumography (IP) technique using four skin electrodes and a small body-worn recorder. The aim of EVI is to measure variation in flow–volume curve shapes within 15–45% of the expired volume. It has been demonstrated that normal variations in the curve shapes are mainly caused by comparing different sleep cycles [2], which are reduced in the presence of bronchial obstructions [3]. Inhaled corticosteroid treatment improves expiratory variability index in steroid-naïve asthmatic children aged 4–7 years https://bit.ly/3n4vBT3