'Magic Cream'-All treats, no tricks. The use of topical steroids for the treatment of hypergranulation tissue in burn wounds: A retrospective review. Issue 4 (October 2022)

• Record Type: Journal Article
• Authors: Yuan, Lam Hui; Johar, Fatimah Mat; Sulaiman, Wan Azman Wan
• Is Part Of: Burns open. Volume 6:Issue 4(2022)
• Page Start: 187
• Page End: 191
• Publication Date: 2022-10
• Subjects: Granulation tissue -- Burn -- Wound healing -- Corticosteroids; Burns and scalds -- Treatment -- Periodicals; Burns and scalds -- Periodicals; Burns and scalds -- Prevention -- Periodicals; Burns and scalds -- Patients -- Rehabilitation -- Periodicals; Burns and scalds -- Nursing -- Periodicals; Burns; Periodicals; Electronic journals; 617.11005
• DOI: 10.1016/j.burnso.2022.10.001
• Languages: English
• ISSNs: 2468-9122

Abstract

Highlights: Hypergranulation tissue will impair the complete wound healing of burn wounds. Topical steroids are useful for treating hypergranulation in burn wounds. 'Magic cream' is name of regime used by our unit to treat hypergranulation tissue. 'Magic cream' consists of topical hydrocortisone 1% w/w cream and topical chloramphenicol 1% w/w cream in 1:1 ratio. It is a simple, cost-effective, and applicable to treat hypergranulation burn wounds on an outpatient basis. Abstract: Hypergranulation, also known as overgranulation, occurs when there is more granulation tissue than required to fill the wound bed and the depth of the wound surface [1]. The presence of hypergranulation tissue in burn injury is rare, but it can impede wound healing and contribute to hypertrophic scarring and contractures. Although silver nitrate cauterization, hypertonic saline, and topical corticosteroids have been used, there was little evidence that optimal hypergranulation tissue treatment for burns exists. The focus of this study was to assess the management of overgranulation tissue in an outpatient context using 'magic cream, ' derived from the experience as a tertiary center in Malaysia. We did a retrospective analysis at the Hospital University Science Malaysia's Plastic and Reconstructive Surgery Department between 2017 and 2021. Forty-seven cases were treated for hypergranulation wounds out of 725 cases. This group of patients had superficial partial thickness to full-thickness dermal burns with a total body surface area (TBSA) ranging from 2 % to 50 %. All patients were educated on how to use 'Magic Cream, ' a home-applied combination of topical hydrocortisone 1 % w/w cream and topical chloramphenicol 1 % w/w cream. The progress of the wound will be monitored closely by weekly inspection in our outpatient unit. All cases showed complete regression of hypergranulation tissue within 1 to 2 weeks without the treatment's local and systemic side effects.