Refractory pyoderma gangrenosum treated with infliximab in an infant. (1st April 2014)

• Record Type: Journal Article
• Authors: Campos‐Muñoz, L.; Conde‐Taboada, A.; Aleo, E.; Toledano, E.; López‐Bran, E.
• Is Part Of: Clinical and experimental dermatology. Volume 39:Number 3(2014)
• Page Start: 336
• Page End: 339
• Publication Date: 2014-04-01
• Subjects: Skin -- Diseases -- Periodicals; 616.5
• DOI: 10.1111/ced.12297
• Languages: English
• ISSNs: 0307-6938

Abstract

Summary: We report the case of an 11‐month‐old boy with severe recalcitrant pyoderma gangrenosum refractory to prednisone, dapsone and ciclosporin. Treatment with infliximab was well tolerated, and resulted in an excellent clinical response that has been sustained for 15 months. The characteristics of this condition in children and the use of infliximab in infants are both reviewed.