Survival of Patient With Hemorrhagic Meningitis Associated With Inhalation Anthrax. (17th October 2022)

• Record Type: Journal Article
• Authors: Lombarte Espinosa, Evelyn; Villuendas Usón, María Cruz; Arribas García, Jorge; Jado García, Isabel; Huarte Lacunza, Rafael; Zárate Chug, Paola; Claraco Vega, Luis Manuel; Jesús Santed Andrés, María; Ríos, María Jiménez; Cook, Rachel; Simard, J Marc; Boyer, Anne E; Rezusta, Antonio
• Is Part Of: Clinical infectious diseases. Volume 75(2022)Supplement 3
• Page Start: S364
• Page End: S372
• Publication Date: 2022-10-17
• Subjects: anthrax -- meningitis -- inhalation anthrax -- antitoxin -- Bacillus anthracis; Communicable diseases -- Periodicals; 616.905
• DOI: 10.1093/cid/ciac531
• Languages: English
• ISSNs: 1058-4838

Abstract

Abstract: This report describes a 49-year-old male construction worker who acquired a Bacillus anthracis infection after working on a sheep farm. He experienced a severe respiratory infection, septic shock, and hemorrhagic meningoencephalitis with severe intracranial hypertension. After several weeks with multiple organ dysfunction syndrome, he responded favorably to antibiotic treatment. Three weeks into his hospitalization, an intracranial hemorrhage and cerebral edema led to an abrupt deterioration in his neurological status. A single dose of raxibacumab was added to his antimicrobial regimen on hospital day 27. His overall status, both clinical and radiographic, improved within a few days. He was discharged 2 months after admission and appears to have fully recovered.