Hypersensitivity reactions to proton pump inhibitors in childhood. (24th November 2020)

• Record Type: Journal Article
• Authors: Mori, Francesca; Franceschini, Fabrizio; Saretta, Francesca; Bianchi, Annamaria; Bottau, Paolo; Caimmi, Silvia; Crisafulli, Giuseppe; Liotti, Lucia; Paglialunga, Claudia; Caffarelli, Carlo
• Editors: Marseglia, Gian Luigi
• Other Names: Marseglia Gian Luigi guestEditor.
• Is Part Of: Pediatric allergy and immunology. Volume 31(2020)Supplement 26
• Page Start: 29
• Page End: 32
• Publication Date: 2020-11-24
• Subjects: childhood -- drug hypersensitivity -- proton pump inhibitors; Allergy in children -- Periodicals; Immunologic diseases in children -- Periodicals; 617
• DOI: 10.1111/pai.13345
• Languages: English
• ISSNs: 0905-6157

Abstract

Abstract: Hypersensitivity reactions (HRs) to proton pump inhibitors (PPIs) are mainly described in adults. Anyway, increased use of PPIs in childhood has been observed in recent years. In the literature, only case reports are published on children. Most of the PPI HRs are IgE‐mediated. Skin test concentrations and allergy workup protocols used for adults are also applied in children. This study underlies that multicentric pediatric studies focusing on PPI reactions in children are needed.