Allergen immunotherapy in atopic dermatitis: Light and shadow in children. (24th November 2020)

• Record Type: Journal Article
• Authors: Caminiti, Lucia; Panasiti, Ilenia; Landi, Massimo; De Filippo, Maria; Olcese, Roberta; Ciprandi, Giorgio; Vernich, Mario; Carelli, Francesco; Votto, Martina; Barberi, Salvatore
• Editors: Eigenmann, Philippe
• Other Names: Marseglia Gian Luigi guestEditor.
• Is Part Of: Pediatric allergy and immunology. Volume 31(2020)Supplement 26
• Page Start: 46
• Page End: 48
• Publication Date: 2020-11-24
• Subjects: allergic immunotherapy -- Atopic dermatitis -- children; Allergy in children -- Periodicals; Immunologic diseases in children -- Periodicals; 617
• DOI: 10.1111/pai.13390
• Languages: English
• ISSNs: 0905-6157

Abstract

Abstract: Atopic dermatitis (AD) is a chronic remitting‐relapsing inflammatory skin disorder. Due to the multifactorial pathogenesis, there are numerous therapeutic management approaches, mainly based on symptomatic treatments. In recent years, allergen immunotherapy (AIT) has been progressively advanced as targeted disease‐modifying treatment of allergic disease. The most recent guideline from the American Academy of Dermatology concludes that data available do not support its use in AD. The Joint Task Force and The European Academy of Dermatology suggest that clinicians can consider AIT treatment in selected patients characterized by aeroallergen sensitization, prevalently HDM, severe AD, and clinical exacerbation after exposure to the causative allergen. Nevertheless, its role in AD is still under debate, especially in children.