Multifunctional 4D‐Printed Sperm‐Hybrid Microcarriers for Assisted Reproduction (Adv. Mater. 50/2022). Issue 50 (16th December 2022)

• Record Type: Journal Article
• Authors: Rajabasadi, Fatemeh; Moreno, Silvia; Fichna, Kristin; Aziz, Azaam; Appelhans, Dietmar; Schmidt, Oliver G.; Medina‐Sánchez, Mariana
• Is Part Of: Advanced materials. Volume 34:Issue 50(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-12-16
• Subjects: 4D‐printing lithography -- assisted fertilization -- biohybrid micromotors -- enzyme‐loaded polymersomes -- multifunctional sperm‐hybrid microcarriers -- targeted cargo‐delivery; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.202270346
• Languages: English
• ISSNs: 0935-9648

Abstract

Abstract : Robotic Microcarriers In article number 2204257, Oliver G. Schmidt, Mariana Medina‐Sánchez, and co‐workers report the development of 4D‐printed multifunctional sperm‐hybrid microcarriers containing soft and smart materials made with two‐photon lithography. These multifunctional facets enable in situ sperm capacitation/hyperactivation, and the local degradation of the cumulus complex that surrounds the oocyte, both to facilitate the sperm–oocyte interaction for the ultimate goal of in vivo assisted fertilization.