Diagnosis and management of food allergy‐associated gastroesophageal reflux disease in young children—EAACI position paper. Issue 10 (17th October 2022)

• Record Type: Journal Article
• Authors: Meyer, Rosan; Vandenplas, Yvan; Lozinsky, Adriana Chebar; Vieira, Mario C.; Canani, Roberto Berni; Dupont, Christophe; Uysal, Pinar; Cavkaytar, Ozlem; Knibb, Rebecca; Fleischer, David M.; Nowak‐Wegrzyn, Anna; Venter, Carina
• Is Part Of: Pediatric allergy and immunology. Volume 33:Issue 10(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-10-17
• Subjects: amino acid formula -- cow milk allergy -- extensively hydrolysed formula -- gastroesophageal reflux -- infants -- non‐IgE mediated food allergy; Allergy in children -- Periodicals; Immunologic diseases in children -- Periodicals; 617
• DOI: 10.1111/pai.13856
• Languages: English
• ISSNs: 0905-6157

Abstract

Abstract: Gastro‐oesophageal reflux (GOR) and food allergy (FA) are common conditions, especially during the first 12 months of life. When GOR leads to troublesome symptoms, that affect the daily functioning of the infant and family, it is referred to as GOR disease (GORD). The role of food allergens as a cause of GORD remains controversial. This European Academy of Allergy and Clinical Immunology (EAACI) position paper aims to review the evidence for FA‐associated GORD in young children and translate this into clinical practice that guides healthcare professionals through the diagnosis of suspected FA‐associated GORD and medical and dietary management. The task force (TF) on non‐IgE mediated allergy consists of EAACI experts in paediatric gastroenterology, allergy, dietetics and psychology from Europe, United Kingdom, United States, Turkey and Brazil. Six clinical questions were formulated, amended and approved by the TF to guide this publication. A systematic literature search using PubMed, Cochrane and EMBASE databases (until June 2021) using predefined inclusion criteria based on the 6 questions was used. The TF also gained access to the database from the European Society of Paediatric Gastroenterology and Hepatology working group, who published guidelines on GORD and ensured that all publications used within that position paper were included. For each of the 6 questions, practice points were formulated, followed by a modified Delphi method consisting of anonymous web‐based voting that was repeated with modified practice points where required, until at least 80% consensus for each practice point was achieved. This TF position paper shares the process, the discussion and consensus on all practice points on FA‐associated GORD.