Synthesis of acridines via copper-catalyzed amination/annulation cascades between arylboronic acids and anthranils. Issue 48 (28th November 2022)

• Record Type: Journal Article
• Authors: Li, Yuge; Xu, Liang; Wei, Yu
• Is Part Of: Organic & biomolecular chemistry. Volume 20:Issue 48(2022)
• Page Start: 9742
• Page End: 9745
• Publication Date: 2022-11-28
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/d2ob01705a
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : The direct conversion of aryl boronic acids and anthranils to acridines has been realized herein, via the catalysis of copper species under acidic conditions. Abstract : Copper-catalyzed tandem cyclization reactions between arylboronic acids and anthranils have been established, providing new approaches for one-pot assembly of azacycle acridines. This one-pot protocol features simple operation, precious-metal-free conditions and good functional group compatibility, thus providing an efficient approach for the synthesis of a variety of acridines in moderate to good yields.