An easy and regioselective synthesis of new functionalized isoxazoline derivatives via a 1, 3-dipolar cycloaddition reaction. Issue 24 (17th December 2022) - Messaoudi, Chaima
Abstract: An efficient and original synthesis of various aminophosphonate-containing isoxazoline derivatives is reported. A library of variously substituted compounds was readily synthesized via a 1, 3-dipolar cycloaddition reaction of β-ethoxycarbonyl N -methylphosphonated allylic amines used as dipolarophiles with chloroximes under mild conditions. Graphical Abstract: UF0001