Silica nanoparticle remodeling under mild conditions: versatile one step conversion of mesoporous to hollow nanoparticles with simultaneous payload loading. Issue 47 (21st November 2022)

• Record Type: Journal Article
• Authors: Shaffer, Cassandra C.; Zhai, Canjia; Chasteen, Jordan L.; Orlova, Tatyana; Zhukovskyi, Maksym; Smith, Bradley D.
• Is Part Of: Nanoscale. Volume 14:Issue 47(2022)
• Page Start: 17514
• Page End: 17518
• Publication Date: 2022-11-21
• Subjects: Nanoscience -- Periodicals; Nanotechnology -- Periodicals; 620.505
• DOI: 10.1039/d2nr05528g
• Languages: English
• ISSNs: 2040-3364

Abstract

Abstract : Applying mild heat to a binary mixture of mesoporous silica nanoparticles (SNPs) plus organic polyammonium additive (dye or drug) cleanly produces hollow nanoparticles with the additive in the remodeled silica shell. Abstract : A binary mixture of mesoporous silica nanoparticles plus organic polyammonium additive (dye or drug) is cleanly converted upon mild heating into hollow nanoparticles. The remodeled nanoparticle shell is an organized nanoscale assembly of globular additive/silica subunits and cancer cell assays show that a loaded drug additive is bioavailable.