Maximizing lymph node dissection from fresh lung cancer specimens. (5th December 2022)

• Record Type: Journal Article
• Authors: Raymond, Cédric; Vieira, Arthur; Joubert, Philippe; Ugalde, Paula A
• Is Part Of: European journal of cardio-thoracic surgery. Volume 63:Number 1(2023)
• Publication Date: 2022-12-05
• Subjects: Specimen handling -- Lung cancer -- Lung cancer staging; Heart -- Surgery -- Periodicals; Chest -- Surgery -- Periodicals; 617.54
• DOI: 10.1093/ejcts/ezac554
• Languages: English
• ISSNs: 1010-7940

Abstract

Abstract: Evaluation of lymph nodes during lung cancer resection is essential for pathologic staging and adjuvant treatment decisions. We developed a standardized approach for grossing resected lobes and segments to better assign the N1 category to hilar and peripheral lymph nodes. Lung specimens were dissected centrifugally from the bronchial stump, and all lymph nodes at the segmental and subsegmental bifurcations were removed. When combined with mediastinal lymph node dissection, this approach will likely maximize the number of lymph nodes analysed and improve the accuracy of pathologic N descriptor classification. Abstract : Anatomic lung resection with systematic lymph node (LN) dissection is the standard of care for patients with clinical stage I or II non-small-cell lung cancer, and radical LN dissection seems to offer the best oncological outcomes [1].