La Radioterapia Nel Trattamento Del Carcinoma Della Prostata: Indicazioni, Evoluzione Tecnologica e Approcci Integrati. Issue 3 (July 2013)

• Record Type: Journal Article
• Authors: Mantini, Giovanna; Alitto, Anna Rita; Fionda, Bruno; Frascino, Vincenzo; Mattiucci, Gian Carlo; Balducci, Mario; Morganti, Alessio Giuseppe; Valentini, Vincenzo
• Is Part Of: Urologia journal. Volume 80:Issue 3(2013)
• Page Start: 188
• Page End: 201
• Publication Date: 2013-07
• Subjects: Review -- prostate cancer radiotherapy -- Dose escalation -- IGRT -- Brachitherapy -- Hypofractionation -- Revisione -- Raditerapia nel tumore della prostata -- Aumento della dose -- Radioterapia guidata dalle immagini -- Brachiterapia -- Ipofrazionamento; Urology -- Periodicals; 616.6005
• DOI: 10.5301/RU.2013.11499
• Languages: English
• ISSNs: 0391-5603

Abstract

Prostate cancer is a heterogeneous, indolent or sometimes aggressive tumor. Treatment options are various and without proved superiority. Radiotherapy (RT) plays a key role in the disease history. Technological evolution with Intensity Modulate Radiation Therapy (IMRT) and Image Guided Radiation Therapy (IGRT) allowed improvement, with significant results on local control and survival. Hypofractionation, Stereotactic Body RT (SBRT) and new brachytherapy approachs are still under investigation, with promising opportunities. Adjuvant vs salvage postoperative RT, hormone association, prophylactic pelvic irradiation are still under debate, but guidelines express overlapping indications. Multidisciplinary managements will be the future for care optimization, providing the best tool for holistic and informed patients' choice.