Anabolic–androgenic steroid abuse and testicular function in men; recent insights. (December 2022)

• Record Type: Journal Article
• Authors: de Ronde, Willem; Smit, Diederik L.
• Is Part Of: Current opinion in pharmacology. Volume 67(2022)
• Publication Date: 2022-12
• Subjects: Pharmacology -- Periodicals; Pharmaceutical Preparations -- Periodicals; Drug Therapy -- Periodicals; Biopharmaceutics -- Periodicals; Pharmacologie -- Périodiques; Pharmacology; Periodicals; 615.105
• DOI: 10.1016/j.coph.2022.102318
• Languages: English
• ISSNs: 1471-4892

Abstract

Abstract: The use of illegal androgens by young men is not uncommon. The majority of users take multiple courses of androgens during their lifetime, leading to a high cumulative exposure. An inseparable side effect is suppression of gonadal function. Although this usually recovers, recovery can take a long time and is not without symptoms. This review focusses on recent studies that have greatly increased our knowledge of the disruption and recovery of testicular function during and after androgen abuse. For the guidance and treatment of (potential) users, in-depth knowledge of this is indispensable.