A service evaluation of patient care relating toClostridioides difficile infection (CDI) in Oxford University Hospital NHS Foundation. (30th November 2022)

• Record Type: Journal Article
• Authors: Katsiroumpas, E; Dunsmure, L; Lim, R
• Is Part Of: International journal of pharmacy practice. Volume 30(2022)Supplement 2
• Page Start: ii25
• Page End: ii26
• Publication Date: 2022-11-30
• Subjects: Clostridioides difficile -- infection prevention and control -- service improvement -- function resonance analysis method; Pharmacy -- Practice -- Periodicals; 615.1
• DOI: 10.1093/ijpp/riac089.029
• Languages: English
• ISSNs: 0961-7671

Abstract

Abstract: Introduction: The bacterium Clostridioides difficile (C. difficile ) frequently colonises the human intestine. In an adult who is healthy, this organism is relatively harmless. However, disruption of the normal gut flora, which is frequently brought on by the use of antibiotics, can result in C lostridioides difficile (C. difficile ) infection (CDI). As a result, C. difficile can grow and produce a toxin that causes diarrhoea. Due to the ease with which C. difficile can be spread in healthcare environments, it is essential to recognise and treat CDI patients as soon as possible and in accordance with best practises. Aim: This service evaluation aimed to explore and understand how adult inpatients presenting with diarrhoea where (CDI is suspected are managed according to Trust Clostridioides difficile guidelines. Methods: Purposive sampling of up to 100 adult inpatients presenting with diarrhoea where C. difficile is suspected and the patient has been an in-patient for least 48 hours post sample request. A data collection tool was developed, pilot tested and used to collect patient data from the Oxford University Hospital's Electronic Prescribing Record. Data was analysed using descriptive statistics and the Functional Resonance Analysis Method (FRAM) that involved 1) Identifying and describing key functions relating to the management of patients 2) Identifying variability in performing key functions and 3) Determine the possibility of function resonance. Ethical approval was obtained from University of Reading. Results: Fifty patient records were accessed. The results showed that many patients had a stool sample sent for review as soon as possible, a clinical review of their condition and where there was the absence of a strong suspicion or strong evidence of C. Difficile a delay in the initiation of empirical therapy. Documentation was an area with poor compliance to guidelines. 50 % had a Bristol stool chart completed before sample sent and after CDI suspected, 60 % had isolation of the patient documented, 47 % had placement of contact precautions documented, and 20 % had documentation of discontinuation of empirical therapy. A FRAM model was developed and a total of 14 functions were identified with three functions "Record Bristol stool charts", "clinical review of the patient", and "placement of contact precautions" being most connected to the other functions, demonstrating the significance of these functions in the management of patients who are suspected of having CDI. Discussion/Conclusion: The three key tasks outlined by FRAM are important to ensure that provide patients with the best care. Understanding variability in how the functions identified in FRAM are performed is important to understand how work is performed in order to then design ways of working that benefits both patients and HCPs. Further work is required to explore this area.