S53 What should we measure in physiotherapy research for bronchiectasis? Qualitative interviews to inform the development of a core outcomes set. (11th November 2022)

• Record Type: Journal Article
• Authors: Hamzeh, H; Spencer, S; Kelly, C
• Is Part Of: Thorax. Volume 77(2022)Supplement 1
• Page Start: A35
• Page End: A35
• Publication Date: 2022-11-11
• Subjects: Chest -- Diseases -- Periodicals; Thorax; Chest -- Diseases; Periodicals; Periodicals; 617.54
• DOI: 10.1136/thorax-2022-BTSabstracts.59
• Languages: English
• ISSNs: 0040-6376

Abstract

Abstract : Introduction: Physiotherapy is a recommended treatment for bronchiectasis, but evidence of effectiveness is unclear partly due to variable selection of outcome measures and inconsistent reporting. 1 To address this, the COS-PHyBE study is developing a core outcome set (COS) for physiotherapy research in adults with bronchiectasis. 2 The COS will identify a minimum group of outcomes for use in clinical trials of physiotherapy. The COS should reflect the views of all stakeholders, including patients and clinicians. The qualitative interview study reported here comprises part of the first stage of COS development. Methods: The sample included adult patients diagnosed with bronchiectasis and previously treated with physiotherapy, as well as physiotherapists clinically involved in bronchiectasis care. Participants were recruited online through patient and professional organisations and social media. All interviews were conducted via video conferencing. Semi structured interviews aimed to elicit outcomes important to participants, using interview prompts. Interviews were digitally recorded, transcribed verbatim and thematic analysis used to identify, classify, prioritise, and explain the significance of outcomes. Results: A total of 18 interviews were conducted. Participants were from 4 countries and different settings, and with various backgrounds and experiences. A total of 70 outcomes of importance to patients and physiotherapists were elicited through the semi structured qualitative interviews, they were grouped into 15 domains ( table 1 ). Thematic analysis revealed exacerbations, quality of life, use of healthcare resources, patient reported symptoms, physical functioning, and sputum as the prominent themes reported by both groups. Conclusions: This qualitative study highlighted the importance of considering stakeholders perspectives when planning research trials. Outcomes identified in this study will be used to inform the next phase of COS development; the international Delphi consensus study. References: Polverino E, Goeminne P, McDonnell M, et.al . European Respiratory Society guidelines for the management of adult bronchiectasis. European Respiratory Journal 2017;50 (3) Hamzeh H, Spencer S, Kelly C. Development of a core outcome set and outcome measurement set for physiotherapy trials in adults with Bronchiectasis (COS-PHyBE study): A protocol. PLOS One 2022;17 (2): e0263695.