The case for simplifying and using absolute targets for viral hepatitis elimination goals. Issue 1 (4th November 2020)

• Record Type: Journal Article
• Other Names: Razavi Homie investigator.; Blach Sarah investigator.; Razavi-Shearer Devin investigator.; Abaalkhail Faisal investigator.; Abbas Zaigham investigator.; Abdallah Ayat investigator.; Abrao Ferreira Paulo investigator.; Abu Raddad Laith Jamal investigator.; Adda Danjuma investigator.; Agarwal Kosh investigator.; Aghemo Alessio investigator.; Ahmed Aijaz investigator.; Al‐Busafi Said A investigator.; Al‐hamoudi Waleed investigator.; Al‐Kaabi Saad investigator.; Al‐Romaihi Hamad investigator.; Aljarallah Badr investigator.; AlNaamani Khalid investigator.; Alqahtani Saleh investigator.; Alswat Khalid investigator.; Altraif Ibrahim investigator.; Asselah Tarik investigator.; Bacon Bruce investigator.; Bessone Fernando investigator.; Bizri Abdul Rahman investigator.; Block Tim investigator.; Bonino Ferruccio investigator.; Brandão‐Mello Carlos Eduardo investigator.; Brown Kimberly investigator.; Bruggmann Philip investigator.; Brunetto Maurizia Rossana investigator.; Buti Maria investigator.; Cabezas Joaquín investigator.; Calleja Jose Luis investigator.; Castro Batänjer Erika investigator.; Chan Henry Lik‐Yuen investigator.; Chang Henry investigator.; Chen Chien‐Jen investigator.; Christensen Peer Brehm investigator.; Chuang Wan‐Long investigator.; Cisneros Laura investigator.; Cohen Chari investigator.; Colombo Massimo investigator.; Conway Brian investigator.; Cooper Curtis investigator.; Craxi Antonio investigator.; Crespo Javier investigator.; Croes Esther investigator.; Cryer Donna investigator.; Cupertino de Barros Fernando Passos investigator.; Derbala Moutaz investigator.; Dillon John investigator.; Doss Wahid investigator.; Dou Xiaoguang investigator.; Doyle Joseph investigator.; Duberg Ann‐Sofi investigator.; Dugan Ellen investigator.; Dunn Rick investigator.; Dusheiko Geoffrey investigator.; El Khayat Hisham investigator.; El‐Sayed Manal H investigator.; Eshraghian Ahad investigator.; Esmat Gamal investigator.; Esteban Mur Rafael investigator.; Ezzat Sameera investigator.; Falconer Karolin investigator.; Fassio Eduardo investigator.; Ferrinho Paulo investigator.; Flamm Steven investigator.; Flisiak Robert investigator.; Foster Graham investigator.; Fung James investigator.; García‐Samaniego Javier investigator.; Gish Robert G investigator.; Gonçales Fernando investigator.; Halota Waldemar investigator.; Hamoudi Waseem investigator.; Hassany Mohamed investigator.; Hatzakis Angelos investigator.; Hay Susan investigator.; Himatt Sayed investigator.; Hoepelman I. M. investigator.; Hsu Yao‐Chun investigator.; Hui Yee Tak investigator.; Hunyady Bela investigator.; Jacobson Ira investigator.; Janjua Naveed investigator.; Janssen Harry investigator.; Jarcuska Peter investigator.; Kabagambe Kenneth investigator.; Kanto Tatsuya investigator.; Kao Jia‐Horng investigator.; Kaymakoglu Sabahattin investigator.; Kershenobich David investigator.; Khamis Faryal investigator.; Kim Dong Joon investigator.; Kim Do Young investigator.; Kondili Loreta A investigator.; Kottilil Shyamasundaran investigator.; Kramvis Anna investigator.; Kugelmas Marcelo investigator.; Kurosaki Masayuki investigator.; Lacombe Karine investigator.; Lagging Martin investigator.; Lao Wai‐Cheung investigator.; Lavanchy Daniel investigator.; Lazarus Jeffrey V. investigator.; Lee Alice investigator.; Lee Samual S investigator.; Levy Miriam investigator.; Liakina Valentina investigator.; Lim Young‐Suk investigator.; Liu Shuang investigator.; Maddrey Willis investigator.; Malekzadeh Reza investigator.; Marinho Rui Tato investigator.; Mathur Poonam investigator.; Maticic Mojca investigator.; Mendes Correa Maria Cassia investigator.; Mera Jorge investigator.; Merat Shahin investigator.; Mogawer Sherif investigator.; Mohamed Rosmawati investigator.; Muellhaupt Beat investigator.; Muljono David investigator.; Mostafa Ibrahim investigator.; Nahum Mendez Sanchez investigator.; Nawaz Arif investigator.; Negro Francesco investigator.; Ninburg Michael investigator.; Ning Qing investigator.; Ntiri‐ Reid Boatemaa investigator.; Nymadawa Pagbajabyn investigator.; Oevrehus Anne investigator.; Ormeci Necati investigator.; Orrego Mauricio investigator.; Osman Alaa investigator.; Oyunsuren Tsendsuren investigator.; Pan Calvin investigator.; Papaevangelou Vassiliki investigator.; Papatheodoridis George investigator.; Popping Stephanie investigator.; Prasad Papu investigator.; Prithiviputh Rittoo investigator.; Qureshi Huma investigator.; Ramji Alnoor investigator.; Razavi‐Shearer Kathryn investigator.; Reddy Rajender investigator.; Remak William investigator.; Richter Clemens investigator.; Ridruejo Ezequiel investigator.; Robaeys Geert investigator.; Roberts Stuart investigator.; Roberts Lewis investigator.; Roudot‐Thoraval Françoise investigator.; Saab Sammy investigator.; Said Sanaa investigator.; Salamat Amjad investigator.; Sanai Faisal investigator.; Sanchez‐Avila Juan Francisco investigator.; Schiff Eugene investigator.; Schinazi Raymond investigator.; Sebastiani Giada investigator.; Seguin‐Devaux Carole investigator.; Shanmugam R. P. investigator.; Sharara Ala investigator.; Shilton Sonjelle investigator.; Shouval Daniel investigator.; Sievert William investigator.; Simonova Marieta investigator.; Sohrabpour Amir Ali investigator.; Sonderup Mark investigator.; Soza Alejandro investigator.; Wendy Spearman C investigator.; Steinfurth Nancy investigator.; Sulkowski Mark investigator.; Tan Soek‐Siam investigator.; Tanaka Junko investigator.; Tashi Dhondup investigator.; Thein Hla‐Hla investigator.; Thompson Peyton investigator.; Tolmane Ieva investigator.; Toy Mehlika investigator.; Valantinas Jonas investigator.; Van de Vijver David investigator.; Vélez‐Möller Patricia investigator.; Vince Adriana investigator.; Waked Imam investigator.; Wang Su investigator.; Wedemeyer Heiner investigator.; Wong Vincent investigator.; Xie Qing investigator.; Yamada Seiji investigator.; Yang Hwai‐I investigator.; Yesmembetov Kakharman investigator.; Yilmaz Yusuf investigator.; Younossi Zobair investigator.; Yu Ming‐Lung investigator.; Yuen Man‐Fung investigator.; Yurdaydin Cihan investigator.; Yusuf Aasim investigator.; Zekry Amany investigator.; Zeuzem Stefan investigator.;
• Is Part Of: Journal of viral hepatitis. Volume 28:Issue 1(2021)
• Page Start: 12
• Page End: 19
• Publication Date: 2020-11-04
• Subjects: Hepatitis, Viral -- Periodicals; Hepatitis, Viral, Animal; Hepatitis, Viral, Human; 616.3623
• DOI: 10.1111/jvh.13412
• Languages: English
• ISSNs: 1352-0504

Abstract

Abstract: The 69th World Health Assembly endorsed the Global Health Sector Strategy for Viral Hepatitis, embracing a goal to eliminate hepatitis infection as a public health threat by 2030. This was followed by the World Health Organization's (WHO) global targets for the care and management of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. These announcements and targets were important in raising awareness and calling for action; however, tracking countries' progress towards these elimination goals has provided insights to the limitations of these targets. The existing targets compare a country's progress relative to its 2015 values, penalizing countries who started their programmes prior to 2015, countries with a young population, or countries with a low prevalence. We recommend that (1) WHO simplify the hepatitis elimination targets, (2) change to absolute targets and (3) allow countries to achieve these disease targets with their own service coverage initiatives that will have the maximum impact. The recommended targets are as follows: reduce HCV new chronic cases to ≤5 per 100 000, reduce HBV prevalence among 1‐year‐olds to ≤0.1%, reduce HBV and HCV mortality to ≤5 per 100 000, and demonstrate HBV and HCV year‐to‐year decrease in new HCV‐ and HBV‐related HCC cases. The objective of our recommendations is not to lower expectations or diminish the hepatitis elimination standards, but to provide clearer targets that recognize the past and current elimination efforts by countries, help measure progress towards true elimination, and motivate other countries to follow suit.