How can we improve response assessments in MDS? Strategies to improve response assessment in MDS treatment paradigms. Issue 4 (December 2022)

• Record Type: Journal Article
• Authors: Bejar, Rafael
• Is Part Of: Baillière's best practice and research in clinical haematology. Volume 35:Issue 4(2022)
• Publication Date: 2022-12
• Subjects: Acute myeloid leukemia AML -- Complete remission CR -- Hematologic improvement HI -- International working group IWG -- Marrow CR mCR -- Myelodysplastic syndromes MDS -- Transfusion dependence TD -- Transfusion independence TI; Hematology -- Periodicals; Blood -- Periodicals; Hematologic Diseases -- Periodicals; Electronic journals; 616
• DOI: 10.1016/j.beha.2022.101405
• Languages: English
• ISSNs: 1521-6926

Abstract

Abstract: Evaluating response to treatment in MDS represents a major challenge due to its associated complexity and heterogeneity. Although response criteria have been proposed by the IWG and revised on several occasions, these criteria have limitations. This review has outlined some refinements that can be used to improve response assessment and to ensure the identification of clinically meaningful endpoints.