Acceptorless Dehydrogenation of Alcohols and Transfer Hydrogenation of Aldehydes in Water Using a Single Bifunctional, Bistate, Water‐soluble Ruthenium Catalyst. Issue 23 (5th October 2022)

• Record Type: Journal Article
• Authors: Hazra, Susanta; Nair, Abhishek; Dolui, Pritam; Malik, Ekta; Elias, Anil J.
• Is Part Of: Chemistry, an Asian journal. Volume 17:Issue 23(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-10-05
• Subjects: aqueous medium -- bifunctional -- transfer hydrogenation -- dehydrogenation of alcohols; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/asia.202200883
• Languages: English
• ISSNs: 1861-4728

Abstract

Abstract: A water‐soluble bifunctional, bistate ruthenium catalyst has been developed using the 8‐aminoquinoline ligand which responds to an acid‐base stimuli and is catalytically active for two complementary reactions. The "Ru‐amino state" is highly active for catalytic transfer hydrogenation of various aldehydes using formic acid as the hydrogen source resulting in a range of primary alcohols. On the other hand, the "Ru‐amido state" is active for the acceptorless dehydrogenation of alcohols to yield carboxylate salts or ketones. The reactions can be carried out in air without an inert atmosphere and the products can be purified by simple extraction without the use of any chromatographic techniques. A range of functional groups which include electron‐rich and deficient (hetero)arenes and alkenes, alkynes, halides, esters, cyano, and nitro groups, are all well tolerated, indicating excellent chemoselectivity for transfer hydrogenation. Abstract : A water‐soluble bifunctional, bistate ruthenium catalyst has been developed which is catalytically active for two complementary reactions such as acceptorless dehydrogenation of alcohols and transfer hydrogenation of aldehydes in purely aqueous medium.