Exercise pulmonary haemodynamic response predicts outcomes in fibrotic lung disease. Issue 3 (27th September 2018)

• Record Type: Journal Article
• Authors: Jose, Arun; King, Christopher S.; Shlobin, Oksana A.; Brown, A. Whitney; Wang, Chengxi; Nathan, Steven D.
• Is Part Of: European respiratory journal. Volume 52:Issue 3(2018)
• Publication Date: 2018-09-27
• Subjects: Respiratory organs -- Diseases -- Periodicals; Respiration -- Periodicals; 616.2
• DOI: 10.1183/13993003.01015-2018
• Languages: English
• ISSNs: 0903-1936

Abstract

Pulmonary hypertension is diagnosed by an elevated mean pulmonary arterial pressure (mPAP) during resting right heart catheterisation (RHC) [1]. Although "exercise-induced pulmonary hypertension" is no longer a distinct clinical entity, recently, there has been renewed interest in the prognostic value of pulmonary haemodynamic responses to exercise, particularly in patients with fibrotic lung disease [1–4]. As the optimal use of exercise RHC in this cohort remains unknown, our main objective in this study was to study the relationship between exercise haemodynamics and outcomes in fibrotic lung disease patients [3–7]. Haemodynamic changes with exercise, including ΔmPAP/ΔCO, predict clinical worsening in fibrotic lung disease patients http://ow.ly/uKno30lb5fF