Cellular analysis in bronchoalveolar lavage: inherent limitations of current standard procedure. Issue 6 (1st June 2017)

• Record Type: Journal Article
• Authors: Bollmann, Benjamin-Alexander; Seeliger, Benjamin; Drick, Nora; Welte, Tobias; Gottlieb, Jens T.; Greer, Mark
• Is Part Of: European respiratory journal. Volume 49:Issue 6(2017)
• Publication Date: 2017-06-01
• Subjects: Respiratory organs -- Diseases -- Periodicals; Respiration -- Periodicals; 616.2
• DOI: 10.1183/13993003.01844-2016
• Languages: English
• ISSNs: 0903-1936

Abstract

Bronchoalveolar lavage (BAL) is an established procedure for diagnosing respiratory infections and characterising non-infective lung diseases [1]. Increasingly, emphasis has been placed on BAL cellular composition in the diagnostic algorithms for interstitial lung disease [2] and chronic lung allograft dysfunction following lung transplantation [3]. The "dead-space" concept: bronchoscope size and instillation protocol significantly alter BAL cellular composition http://ow.ly/ZEaj30be7HV