Identification of a novel crizotinib-sensitive BCL11A-ALK gene fusion in a nonsmall cell lung cancer patient. Issue 4 (13th April 2017)

• Record Type: Journal Article
• Authors: Tian, Qing; Deng, Wen-Jing; Li, Zong-Wei
• Is Part Of: European respiratory journal. Volume 49:Issue 4(2017)
• Publication Date: 2017-04-13
• Subjects: Respiratory organs -- Diseases -- Periodicals; Respiration -- Periodicals; 616.2
• DOI: 10.1183/13993003.02149-2016
• Languages: English
• ISSNs: 0903-1936

Abstract

Until now, more than 10 different ALK fusion partners have been discovered in nonsmall cell lung cancer (NSCLC): EML4, KIF5B, KLC1, TFG, TPR, HIP1, STRN, DCTN1, SQSTM1 and BIRC 6, among others [1, 2]. We report here a novel ALK fusion partner in a NSCLC patient who responded well to the ALK inhibitor crizotinib. We report a novel ALK fusion partner in a NSCLC patient who responded well to the ALK inhibitor crizotinib http://ow.ly/7O6f309KyFb