Time to sputum culture conversion and treatment outcome of patients with multidrug-resistant tuberculosis: a prospective cohort study from urban China. Issue 3 (23rd March 2017)

• Record Type: Journal Article
• Authors: Lu, Peng; Liu, Qiao; Martinez, Leonardo; Yang, Haitao; Lu, Wei; Ding, Xiaoyan; Zhu, Limei
• Is Part Of: European respiratory journal. Volume 49:Issue 3(2017)
• Publication Date: 2017-03-23
• Subjects: Respiratory organs -- Diseases -- Periodicals; Respiration -- Periodicals; 616.2
• DOI: 10.1183/13993003.01558-2016
• Languages: English
• ISSNs: 0903-1936

Abstract

Sputum culture plays an important role in monitoring treatment response in patients with multidrug-resistant tuberculosis (MDR-TB), and sputum culture conversion is a clinical tool used to predict therapeutic efficacy [1]. Monthly culture monitoring is essential for earlier detection of treatment failure in patients with MDR-TB. More sensitive signals of nonresponse would further avoid adverse outcomes [2]. The timing of testing for culture conversion has potential as a marker of MDR-TB treatment success http://ow.ly/borO308pPXg