A new two-step algorithm for the treatment of COPD. Issue 2 (9th February 2017)

• Record Type: Journal Article
• Authors: Miravitlles, Marc; Anzueto, Antonio
• Is Part Of: European respiratory journal. Volume 49:Issue 2(2017)
• Publication Date: 2017-02-09
• Subjects: Respiratory organs -- Diseases -- Periodicals; Respiration -- Periodicals; 616.2
• DOI: 10.1183/13993003.02200-2016
• Languages: English
• ISSNs: 0903-1936

Abstract

The pharmacological treatment of chronic obstructive pulmonary disease (COPD) is quite uniformly based on long-acting bronchodilators (LABD), either a long-acting muscarinic antagonist (LAMA) or a long-acting β-agonist (LABA), and inhaled corticosteroids (ICS). Moreover, most patients are eventually treated with a combination of all three (LAMA/LABA/ICS or "triple therapy") irrespective of their severity and level of risk. Furthermore, a large proportion of patients receive triple therapy as the initial treatment [1]. We propose a new simple treatment algorithm based on the severity of symptoms and phenotypes or treatable traits (figure 1). Treatment of COPD can be simplified with a two-step algorithm according to severity and phenotype http://ow.ly/iJUN306DEHU