High burden of prevalent tuberculosis among previously treated people in Southern Africa suggests potential for targeted control interventions. Issue 4 (7th July 2016)

• Record Type: Journal Article
• Authors: Marx, Florian M.; Floyd, Sian; Ayles, Helen; Godfrey-Faussett, Peter; Beyers, Nulda; Cohen, Ted
• Is Part Of: European respiratory journal. Volume 48:Issue 4(2016)
• Page Start: 1227
• Page End: 1230
• Publication Date: 2016-07-07
• Subjects: Respiratory organs -- Diseases -- Periodicals; Respiration -- Periodicals; 616.2
• DOI: 10.1183/13993003.00716-2016
• Languages: English
• ISSNs: 0903-1936

Abstract

Several studies from Southern Africa report a high risk of tuberculosis (TB) among individuals who have previously been treated for the disease compared to those never before treated [1–5]. In high-burden settings, recurrent TB may affect large numbers of individuals even after successful treatment, with exogenous reinfection as an important underlying mechanism [2–4]. For example, in Cape Town, South Africa, a city with a high incidence of TB, previously treated individuals constitute one-third of the burden of notified TB [6]. High TB prevalence in previously treated people suggests potential for targeted interventions in high-burden settings http://ow.ly/ihG83015s4l