Compassionate use of new drugs in children and adolescents with multidrug-resistant and extensively drug-resistant tuberculosis: early experiences and challenges. Issue 3 (23rd June 2016)

• Record Type: Journal Article
• Authors: Tadolini, Marina; Garcia-Prats, Anthony J.; D'Ambrosio, Lia; Hewison, Catherine; Centis, Rosella; Schaaf, H. Simon; Marais, Ben J.; Ferreira, Hannetjie; Caminero, Jose A.; Jonckheere, Sylvie; Sinha, Animesh; Herboczek, Krzysztof; Khaidarkhanova, Zarema; Hayrapetyan, Armen; Khachatryan, Naira; Urtkmelidze, Ia; Loreti, Carolina; Esposito, Susanna; Matteelli, Alberto; Furin, Jennifer; Varaine, Francis; Migliori, Giovanni Battista
• Is Part Of: European respiratory journal. Volume 48:Issue 3(2016)
• Page Start: 938
• Page End: 943
• Publication Date: 2016-06-23
• Subjects: Respiratory organs -- Diseases -- Periodicals; Respiration -- Periodicals; 616.2
• DOI: 10.1183/13993003.00705-2016
• Languages: English
• ISSNs: 0903-1936

Abstract

The World Health Organization (WHO) estimated that 480 000 new multidrug-resistant (MDR) tuberculosis (TB) cases occurred globally in 2014, with 190 000 deaths. Limited data are available on the burden of MDR-TB in children. A recent systematic review estimated that 32 000 children acquire MDR-TB annually; of these, very few are correctly diagnosed and provided with appropriate treatment [1]. First experience and challenges of compassionate use of new anti-TB drugs to treat MDR- and XDR-TB in children http://ow.ly/SWXF300a0UX