Monoallelic germline ATM mutation and organising pneumonia induced by radiation therapy to the breast. Issue 3 (4th February 2016)

• Record Type: Journal Article
• Authors: Cordier, Jean-François; Cottin, Vincent; Lazor, Romain; Stoppa-Lyonnet, Dominique
• Is Part Of: European respiratory journal. Volume 47:Issue 3(2016)
• Page Start: 997
• Page End: 1000
• Publication Date: 2016-02-04
• Subjects: Respiratory organs -- Diseases -- Periodicals; Respiration -- Periodicals; 616.2
• DOI: 10.1183/13993003.01842-2015
• Languages: English
• ISSNs: 0903-1936

Abstract

Organising pneumonia is defined by the presence of intra-alveolar buds consisting of inflammatory cells, fibroblasts and myofibroblasts, and loose connective tissue, often associated with bronchiolitis obliterans. Organising pneumonia may be cryptogenic (idiopathic) or associated with a variety of causes including, especially, infection, adverse reaction to drugs, connective tissue diseases [1] and radiation therapy to the breast [2, 3]. Radiation-induced organised pneumonia may be associated with monoallelic ATM gene mutation http://ow.ly/WIpFe