End TB with precision treatment!. Issue 2 (February 2016)

• Record Type: Journal Article
• Authors: van der Burgt, Evelien P.M.; Sturkenboom, Marieke G.G.; Bolhuis, Mathieu S.; Akkerman, Onno W.; Kosterink, Jos G.W.; de Lange, Wiel C.M.; Cobelens, Frank G.J.; van der Werf, Tjip S.; Alffenaar, Jan-Willem C.
• Is Part Of: European respiratory journal. Volume 47:Issue 2(2016)
• Page Start: 680
• Page End: 682
• Publication Date: 2016-02
• Subjects: Respiratory organs -- Diseases -- Periodicals; Respiration -- Periodicals; 616.2
• DOI: 10.1183/13993003.01285-2015
• Languages: English
• ISSNs: 0903-1936

Abstract

We read with interest the recent Perspective paper by Lönnroth et al. [1] describing a framework for tuberculosis (TB) elimination. In our opinion, monitoring drug exposure by measuring blood concentrations over time (therapeutic drug monitoring (TDM)) may be helpful in contributing to TB elimination in low- and medium-burden setting. TB precision treatment, including optimised drug exposure in relation to drug susceptibility testing, may help end TB http://ow.ly/Utu2u