Neonatal Herpes Simplex Virus: Cutaneous Recurrence Is Common on Stopping Prophylactic Suppression Therapy. Issue 11 (1st September 2022)

• Record Type: Journal Article
• Authors: Waheed, Sabrina; Nuttall, Luke; Fidler, Katy; Dudley, Julia; Bamford, Alasdair; Lyall, Hermione
• Is Part Of: Journal of the Pediatric Infectious Diseases Society. Volume 11:Issue 11(2022)
• Page Start: 518
• Page End: 521
• Publication Date: 2022-09-01
• Subjects: acyclovir -- HSV infection -- neonatal HSV -- prophylaxis -- recurrence -- suppression therapy; Communicable diseases in children -- Periodicals; Children -- Diseases -- Periodicals; 618.929
• DOI: 10.1093/jpids/piac098
• Languages: English
• ISSNs: 2048-7193

Abstract

Abstract: Neonatal herpes simplex virus (HSV) infection is a potentially devastating disease. Data on the recurrence of disease while on suppressive therapy are limited. We reviewed cases of neonatal HSV. Prematurity was associated with more recurrence. No systemic or CNS recurrence occurred, but there were frequent recurrences of skin lesions.