A Re-emergence of Subacute Sclerosing Panencephalitis in the United Kingdom. Issue 1 (12th October 2022)

• Record Type: Journal Article
• Authors: Campbell, Helen; Lopez Bernal, Jamie; Bukasa, Antoaneta; Andrews, Nick; Baker, Elaine; Maunder, Polly; Winstone, Anne Marie; Ramsay, Mary; Verity, Christopher; Brown, Kevin
• Is Part Of: Pediatric infectious disease journal. Volume 42:Issue 1(2023)
• Page Start: 82
• Page End: 84
• Publication Date: 2022-10-12
• Subjects: subacute sclerosing panencephalitis -- measles -- vaccination -- measles-mumps-rubella -- surveillance; Communicable diseases in children -- Periodicals; Infection in children -- Periodicals; 618.929
• DOI: 10.1097/INF.0000000000003744
• Languages: English
• ISSNs: 0891-3668

Abstract

Abstract : New pediatric and adult subacute sclerosing panencephalitis cases between 1996 and 2020 were reported based on an established UK registry with no evidence of under-ascertainment using a separate pediatric surveillance system. After 15 years with no pediatric UK-acquired cases, 3 cases arose from 2017 after increased measles. Modeling suggested this was in line with measles notifications, underreporting of laboratory-confirmed measles or increased subacute sclerosing panencephalitis risk.